The extract comes from Irvingia gabonensis, also known as mango in Africa, a fruit commonly consumed in West Africa. Laboratory research has shown that the seeds of the plant extracts can inhibit the production of fat in the body, its effects on certain genes and enzymes that regulate metabolism.
For the current study randomly researchers at the University of Yaounde in Cameroon assigned 102 obese adults to take either plant extract or a placebo twice daily for 10 weeks. The study participants did not follow a special diet and were encouraged to maintain their normal physical activity level.
After the survey was extracted from group lost a significant amount of weight - on average about 28 pounds - while the placebo group showed virtually no change.
At the same time, showed a decrease in "bad" cholesterol LDL and blood sugar.
Mr. Julio E. Oben and colleagues report the findings online in the journal Lipids in health and disease. The Fairfield, California, Gateway Health Alliance, Inc. provided an extract of Irvingia gabonensis and partly funded the research.
The study is the first well controlled study the effectiveness of extracts from a weight loss aid researchers note. But the results, they write, according to Irving gabonensis could provide a "useful tool" to fight an increasingly global problem of obesity and related disorders.
Some patients have an extract from the adverse effects such as headaches, sleep disturbances and gas, but prices were similar in the placebo group.
The results, the team concludes Oben, should "provide an impetus to many more clinical trials."
SOURCE: lipids in health and disease, the line March 2, 2009.
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